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Last updated on Oct 15, Just lucky. But this advance brings medicine a step closer to addressing what seems to be the root cause of many age-related illnesses. Prednisone and albuterol steroids in asthma medication can cause weight gain as a side effect. This may prevent Advair Osteopenia Osteoporosis from occurring changes in weight increased blood sugar levels (hyperglycemia) Side effects of fluticasone topical sun sensitivity (wear protective clothing, sunscreen) burning, irritation, itching, or dryness. I'm going to my doctor tomorrow and just let him try to tell me that advair doesn't cause weight gain Advair Diskus 100/50, Advair Diskus 250/50, and Advair Diskus 500/50 are combinations of fluticasone propionate and salmeterol xinafoate. If you notice any change in weight while taking Advair, talk with your healthcare provider Advair may cause weight gain in some people. Supplements that build bone: You may find it useful to take a supplement that is known to build bone. 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The increase in weight is probably keflex food interactions due to water retention or changes in fat metabolism. Medically reviewed by Raj Dasgupta, MD Weight gain is possible while taking Advair. I am still trying to figure out why I have trouble breathing when I've never had any medical problems prior to falling ill 3 years ago.